I also had issues with whyem and smoaks mega arsenal, after installing those two mods, ive been stuttering nonstop on horse or everytime I load the world so i had to uninstall the game and do cleanups, went to use LITE instead of OCU, Catalogue Improvements over WhyEM/Smoaks and I even added heavy mods like Terrain Texture Overhaul and Character Overhaul, set the clean state vfs.asi to read mode only and on security tab I placed deny on every user on permissions and Setting the LogLevel to 0 in lml.ini with the new mods loaded and boom, I never got the stuttering again, I really suspected it was my previous save that had the previous mods and the overwritten vfs.asi that caused me stuttering everytime, also I didnt tinker with my in game graphics settings anymore, I only removed motion blur and played